Uncaria tomentosa Family: Rubiaceae
una de gato
Cat's claw is a climbing vine that grows in the high Peruvian tropical forests. Two species, Uncaria tomentosa and Uncaria guianensis, have traditionally been used by the Peruvian Indians to treat arthritis, digestive problems and other ailments. The active ingredients are extracted from the bark and root of the vine. Both types of Uncaria are being evaluated by modern research methods and have been shown to be effective as both an anti-inflammatory and an immune stimulant.
Cats claw is normally taken as a bark decoction (boiling a specific amount of herb in water) and contains different alkaloids (including rhynchophylline and isorhynchophyllin) that have immune stimulating, anti-hypertensive, diuretic and smooth-muscle relaxant effects.
Medically Valid Uses:
Currently, there are no rigorously established uses for cat's claw.
Please note that this section reports on claims that have NOT yet been substantiated through scientific studies.
Evidence indicates that cat's claw is useful for treating certain digestive disturbances. For instance, it may protect the lining of the small intestine from damage done by anti-inflammatory agents such as indomethacin. In addition, pentacyclic oxindole alkaloids found in cat's claw are claimed to modulate the immune system by increasing the activity of white blood cells and increasing the levels of Interleukin-1.
Some claims suggest that cat's claw helps cleanse the intestinal tract and treat some viral infections. Cat's claw is also claimed to have antioxidant, anti-mutagenic (preventing mutation) and anti-inflammatory properties. Other claims even suggest that cat's claw may play a role in treating AIDS and cancer, as well as arthritis and ulcers.
Cat's claw comes in tablets and capsules. Follow packaging instructions for correct dose.
Side Effects, Toxicity and Interactions:
Few side effects are associated with this herbal remedy. Toxicity studies have shown that cat's claw is non-toxic at standard dosing levels. At higher doses, cat's claw is toxic to the kidneys.
Women who are pregnant or breast-feeding should not use cat's claw.
There are no known significant food or drug interactions. In general, alkaloids are absorbed better in an acid environment, so cat's claw should not be taken with antacids.
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Sandoval-Chacon M, Thompson JH, Zhang XJ, et al. Antiinflammatory actions of cat's claw: the role of NF-kappaB. Aliment Pharmacol Ther. 1998;12(12):1279-89.
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Rizzi R, Re F, Bianchi A, et al. Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts. J Ethnopharmacol. 1993;38(1):63-77.